Roybal KT.  Refining Cell Therapy. Science. 2018. 09 Mar 2018: Vol. 359, Issue 6380, pp. 1112-1113.

Roybal KT and Lim WA. Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities. Annu Rev Immunol. 2017. Apr; 35:229-253. PMID:28446063.       View in: Pubmed (Overview of the Current and Future Landscape of Engineered Cell Therapies) 

Rupp LJ, Schumann K, Roybal KT, Gate RE, Ye CJ, Lim WA, Marson A. CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells. Science Reports. 2017 Apr 7;7(1):737. PMID: 28389661. View in: Pubmed

Roybal KT, Williams JZ, Morsut L, Rupp LJ, Kolinko I, Choe JH, Walker WJ, McNally KA, Lim WA. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 2016 Oct 6; 167(2):419-432.e16. PMID: 27693353. View in: PubMed  

FEATURED IN: CellNature Medicine, Nature Reviews Drug Discovery, Forbes 

Roybal KT, Buck TE, Ruan X, Cho BH, Clark DJ, Ambler R, Tunbridge HM, Zhang J, Verkade P, Wülfing C, Murphy RF. Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics. Science Signaling. 2016; 9(424):rs3. PMID: 27095595. View in: PubMed 

Roybal KT, Rupp LJ, Morsut L, Walker WJ, McNally KA, Park JS, Lim WA. Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits. Cell. 2016 Feb 11; 164(4):770-9. PMID: 26830879. View in: PubMed  

FEATURED IN: CellNature Reviews Cancer, Nature Biotechnology, Nature Methods, The Economist  

Morsut L*, Roybal KT*, Xiong X, Gordley RM, Coyle SM, Thomson M, Lim WA. Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors. Cell. 2016 Feb 11; 164(4):780-91. PMID: 26830878. (*co-first authors - equal contribution) View in: PubMed  

FEATURED IN: CellNature Biotechnology, Nature Methods  

Wu CY, Roybal KT, Puchner EM, Onuffer J, Lim WA. Remote control of therapeutic T cells through a small molecule-gated chimeric receptor. Science. 2015 Oct 16; 350(6258):aab4077. PMID: 26405231. View in: PubMed 

Roybal KT, Mace EM, Mantell JM, Verkade P, Orange JS, Wülfing C. Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network. PLoS One. 2015; 10(8):e0133299. PMID: 26237050; PMCID: PMC4523204. View in: PubMed

Roybal KT, Mace EM, Clark DJ, Leard AD, Herman A, Verkade P, Orange JS, Wülfing C. Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling. PLoS One. 2015; 10(8):e0133231. PMID: 26237588; PMCID: PMC4523178. View in: PubMed

Wu CY, Rupp LJ, Roybal KT, Lim WA. Synthetic biology approaches to engineer T cells. Curr Opin Immunol. 2015 Aug; 35:123-30. PMID: 26218616; PMCID: PMC4553068 [Available on 08/01/16]. View in: PubMed

Wülfing C, Roybal KT. Cellular structures controlling T cell signaling in time and space. Encyclopedia of Cell Biology. 2015; 677-686. View Publication

Huber JP, Gonzales-van Horn SR, Roybal KT, Gill MA, Farrar JD. IFN-a suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells. J Immunol. 2014 Jun 15; 192(12):5687-94. PMID: 24813204; PMCID: PMC4104489. View in: PubMed

Furlan SN, Mandraju R, Brewer T, Roybal KT, Troutman TD, Hu W, Palm NW, Unni A, Pasare C. Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors. MAbs. 2014 Jan-Feb; 6(1):108-18. PMID: 24284965; PMCID: PMC3929435. View in: PubMed

Roybal KT, Sinai P, Verkade P, Murphy RF, Wülfing C. The actin-driven spatiotemporal organization of T-cell signaling at the system scale. Immunol Rev. 2013 Nov; 256(1):133-47. PMID: 24117818. View in: PubMed

Falcon E, Ozburn A, Mukherjee S, Roybal KT, McClung CA. Differential regulation of the period genes in striatal regions following cocaine exposure. PLoS One. 2013; 8(6):e66438. PMID: 23776671; PMCID: PMC3679086. View in: PubMed

Roybal KT, Wülfing C. New TACTICS for finding Numb. Immunol Cell Biol. 2013 Jan; 91(1):1-2. PMID: 23183270. View in: PubMed

Eitson JL, Medeiros JJ, Hoover AR, Srivastava S, Roybal KT, Aínsa JA, Hansen EJ, Gumbo T, van Oers NS. Mycobacterial shuttle vectors designed for high-level protein expression in infected macrophages. Appl Environ Microbiol. 2012 Oct; 78(19):6829-37. PMID: 22820329; PMCID: PMC3457510. View in: PubMed

DeFord-Watts LM, Dougall DS, Belkaya S, Johnson BA, Eitson JL, Roybal KT, Barylko B, Albanesi JP, Wülfing C, van Oers NS. The CD3 zeta subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse. J Immunol. 2011 Jun 15; 186(12):6839-47. PMID: 21543646; PMCID: PMC3110614 View in: PubMed

Sinai P, Roybal KT, Wülfing C. Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacy. Commun Integr Biol. 2010 Nov; 3(6):545-8. PMID: 21331235; PMCID: PMC3038059. View in: PubMed

Roybal KT, Wülfing C. Inhibiting the inhibitor of the inhibitor: blocking PKC-theta to enhance regulatory T cell function. Science Signaling. 2010; 3(132):pe24. PMID: 20664063.  View in: PubMed

Singleton KL, Roybal KT, Sun Y, Fu G, Gascoigne NR, van Oers NS, Wülfing C. Spatiotemporal patterning during T cell activation is highly diverse. Science Signaling. 2009; 2(65):ra15. PMID: 19351954; PMCID: PMC2694444. View in: PubMed

Roybal KT, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA, McClung CA. Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15):6406-11. PMID: 17379666; PMCID: PMC1851061. View in: PubMed